Orlistat vs Saxenda: Can you take Orlistat and Saxenda together?

There are no known drug interactions between Orlistat and Saxenda®. However, Orlistat can interact with other drugs, such as certain immunosuppressant medications and warfarin (Coumadin®), as well as impair the absorption of fat-soluble vitamins (A, D, E, and K). Orlistat is a medication that is FDA-approved for weight loss and is available over-the-counter as Alli® and by prescription as Xenical®. Orlistat works by blocking the absorption of dietary fat from foods thereby reducing calorie intake to facilitate weight loss. In certain situations, combinations of weight loss medications – like taking  Orlistat and Saxenda together – might be recommended by your doctor. Deciding whether or not to start a new medication (even if sold over-the-counter) should be discussed with your doctor. In addition to other medications, be mindful of what foods you consume while you’re taking Saxenda, too.

Learn more about how Form Health doctors prescribe Saxenda for weight loss to help patients achieve their goals.

ABOUT THE AUTHOR

Brooke Marsico, PA-C

Brooke Marsico completed her physician assistant training at Midwestern University in 2011. She began her practice in the field of Obesity Medicine at Northwestern Memorial Hospital in Chicago where she practiced from 2016 to 2021. She went on to treat patients living with obesity at Cleveland Clinic from 2021 to 2022 prior to joining the team at Form Health. Brooke is passionate about helping patients living with obesity achieve meaningful weight loss and improve their health. Her practice focuses on individualized behavioral and pharmacological intervention to help patients reach their goals. She is also experienced in managing patients who have a history of bariatric surgery.

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Disclaimer: The content made available on The Form Health Website represents the views and opinions of the authors and not those of other entities, such as the manufacturers of products mentioned therein.  

Saxenda® is a registered trademark of Novo Nordisk A/S.
Alli® is a registered trademark of Haleon.
Xenical® is a registered trademark of H2 Pharma.